SOP for Preparation of 2.5% w/v Caustic soda solution

The purpose of this standard Operating Procedure (SOP) is to lay down a procedure for preparation of 2.5% w/v caustic soda solution.

This procedure is applicable for preparation of caustic soda solution used for cleaning of equipment and accessories in pellet section at manufacturing facility of Pharmaceutical   Industry.

  • PROCEDURE:
    • PREPARATION OF 2.5 % W/V CAUSTIC SODA SOLUTION:
      • Take the necessary acessoceries such as SS container, acid – alkali proof gloves and safety goggles.
      • Take 10 lt. Purified water in a clean SS container.
      • Take 250.00 Gms of Sodium Hydroxide pellets and add it into purified water slowly. Then mix this gently using SS spatula and keep it aside for five minutes for cooling.
      • Label the prepared solution properly.
      • After the completion of the operation destroy the remaining cleaning solution by diluting sufficiently and pouring into drain in washing area.
      • Use freshly prepared caustic soda solution only.
  • TRAINING:
  • As per SOP On Employee Training
  • ANNEXURE:

Annexure I    : Record of 2.5 % w/v Caustic Soda Solution Preparation and     Destruction of Unused Solution.

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